Spursil Columns

• Combine high purity silica with unique polar modification technology
• Unique selectivity and enhanced resolution
• Silanol shielding for excellent peak shape
• Improved water wettability and stable retention in highly aqueous mobile phase conditions
• Excellent retention for polar compounds
• Extended range pH stability
• Choose from a variety of selectivities and hardware formats

Spursil™ polar-modified phases are based on ultra high-purity silica and novel polar modification technology. The unique bonded phases maximize polar retention and selectivity, while virtually eliminating silanol activity. The resulting polar-modified packing material contains a surface which is easily "wetted" with polar eluents and can run in highly aqueous conditions. The polar group also seems to play a role in base deactivation. We have seen some evidence that hydrogen bonding occurs between certain polar linkers and the silica surface, thereby decreasing the interaction of such silanols with basic components in the sample. Additionally, polar-modified phases often provide selectivity quite different from standard C18 phases.

Standard reverse phase columns, particularly C18 columns, often suffer from "phase collapse" and the retention of the compounds is severely diminished when used in combination with highly aqueous phases. This phenomenon is substantially reduced with Spursil™ because the polar modifications make the phase less hydrophobic and more wettable. Polar-modified phases remain fully extended in aqueous phases, allowing increased interaction between samples and the bonded phase. Spursil™ columns show good retention of polar compounds which tend to elute in the void volume on standard ODS phases.

Spursil™ columns are available in 3, 5, and 10 micron particle sizes, column lengths are ranging from 30 mm to 250 mm, and column dimensions are ranging from 2 mm to 21.2 mm. Ten micron preparative materials are available in bulk form.

Particle Size (µ) Pore Size A Surface Area m2/g Pore Volume cm3/g Carbon Load PH Range
3 ,5 , 10 100 440 25 1.5 - 10


ADVANCED CHROMATOGRAPHY TECHNOLOGIES PVT LTD. is an instrument representation company in India, distributing the products of various foreign manufactures specializing in CHROMATOGRAPHY Instrumentation.

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    Pharmalytica 2018

  • From 10 Aug 2018 To 11 Aug 2018